Drug General Information
Drug ID	D0SI7S
Former ID	DNC009076
Drug Name	5,6,7,8-tetrahydroanthracene-1,4-dione
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529817]
Structure		Download 2D MOL 3D MOL
Formula	C14H12O2
Canonical SMILES	C1CCC2=C(C1)C=C3C(=O)C=CC(=O)C3=C2
InChI	1S/C14H12O2/c15-13-5-6-14(16)12-8-10-4-2-1-3-9(10)7-11(12)13/h5-8H,1-4H2
InChIKey	DWXLNXHEUIUNRF-UHFFFAOYSA-N
PubChem Compound ID	44582382
Target and Pathway
Target(s)	M-phase inducer phosphatase 2	Target Info	Inhibitor	[529817]
KEGG Pathway	MAPK signaling pathway
	Cell cycle
	Progesterone-mediated oocyte maturation
	MicroRNAs in cancer
NetPath Pathway	IL2 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
	Wnt Signaling Pathway
Pathway Interaction Database	PLK1 signaling events
	FOXM1 transcription factor network
	p38 signaling mediated by MAPKAP kinases
	Aurora A signaling
Reactome	Cyclin B2 mediated events
	Cyclin A/B1 associated events during G2/M transition
	Cyclin A:Cdk2-associated events at S phase entry
WikiPathways	Senescence and Autophagy in Cancer
	MAPK Signaling Pathway
	Retinoblastoma (RB) in Cancer
	Prostate Cancer
	Integrated Breast Cancer Pathway
	Integrated Cancer pathway
	Mitotic G2-G2/M phases
	Cell Cycle
References
Ref 529817	Bioorg Med Chem. 2009 Mar 15;17(6):2276-81. Epub 2008 Nov 8.Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases.
Ref 529817	Bioorg Med Chem. 2009 Mar 15;17(6):2276-81. Epub 2008 Nov 8.Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases.

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