Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0SL8T
|
||||
| Former ID |
DPR000177
|
||||
| Drug Name |
ISIS-FGFR4
|
||||
| Drug Type |
Antisense drug
|
||||
| Indication | Obesity [ICD9: 278; ICD10:E66] | Preclinical | [551052] | ||
| Company |
ISIS Pharm
|
||||
| Target and Pathway | |||||
| Target(s) | mRNA of FGFR4 | Target Info | [551052] | ||
| PANTHER Pathway | FGF signaling pathway | ||||
| Pathway Interaction Database | FGF signaling pathway | ||||
| Reactome | PI3K Cascade | ||||
| PIP3 activates AKT signaling | |||||
| FGFR4 ligand binding and activation | |||||
| Constitutive Signaling by Aberrant PI3K in Cancer | |||||
| Phospholipase C-mediated cascade | |||||
| FRS-mediated FGFR4 signaling | |||||
| SHC-mediated cascade:FGFR4 | |||||
| PI-3K cascade:FGFR4 | |||||
| Negative regulation of FGFR4 signaling | |||||
| RAF/MAP kinase cascade | |||||
| References | |||||
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