Drug General Information
Drug ID
D0SQ0T
Former ID
DNC011538
Drug Name
C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526614]
Structure
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2D MOL

3D MOL

Formula
C7H11N3
Canonical SMILES
C1C(C1C2=CN=CN2)CN
InChI
1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)/t5-,6+/m1/s1
InChIKey
LMFNLINKCDGRTE-RITPCOANSA-N
PubChem Compound ID
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [526614]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 526614J Med Chem. 2003 May 8;46(10):1980-8.Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.
Ref 526614J Med Chem. 2003 May 8;46(10):1980-8.Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.

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