Drug Information

Drug General Information
Drug ID
D0SZ8Q
Former ID
DIB012173
Drug Name
CSC-500297
Synonyms
CSC-500204; CSC-500 series, Cascade; 5-HT2c receptor agonists (obesity/obsessive compulsive disorder), Cascade
Indication Obesity [ICD9: 278; ICD10:E66] Investigative [543963]
Company
Cascade Therapeutics Inc
Target and Pathway
Target(s) 5-hydroxytryptamine 2C receptor Target Info Agonist [543963]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 543963(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 8).
Ref 543963(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 8).

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