Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0TA8F
|
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| Former ID |
DNC013747
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| Drug Name |
(S,S)-oxandrine hydrochloride
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [551356] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C37H39ClN2O7
|
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| Canonical SMILES |
CN1CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C4)OC)C5=C(C=CC(=C5)C(<br />=O)C6C7=CC(=C(C=C7CCN6C)OC)O3)O)O)OC.Cl
|
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| InChI |
1S/C37H38N2O7.ClH/c1-38-12-11-22-18-32(45-5)36(42)37-33(22)27(38)15-20-6-9-29(43-3)26(14-20)25-16-23(7-8-28(25)40)35(41)34-24-19-31(46-37)30(44-4)17-21(24)10-13-39(34)2;/h6-9,14,16-19,27,34,40,42H,10-13,15H2,1-5H3;1H/t27-,34-;/m0./s1
|
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| InChIKey |
HEISNSAKVPLJDD-LUKLCJSZSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Dopamine D1 receptor | Target Info | Inhibitor | [551356] | |
| D(2) dopamine receptor | Target Info | Inhibitor | [551356] | ||
| PANTHER Pathway | Dopamine receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Dopamine receptor mediated signaling pathway | |||||
| Nicotine pharmacodynamics pathway | |||||
| PathWhiz Pathway | Dopamine Activation of Neurological Reward System | ||||
| WikiPathways | Hypothetical Network for Drug Addiction | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Genes and (Common) Pathways Underlying Drug Addiction | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP666:Hypothetical Network for Drug Addiction | |||||
| GPCR downstream signaling | |||||
| Nicotine Activity on Dopaminergic Neurons | |||||
| References | |||||
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