Drug General Information
Drug ID	D0TJ7R
Former ID	DNC007496
Drug Name	1-benzyl-4-phenylpiperidin-4-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528785]
Structure		Download 2D MOL 3D MOL
Formula	C18H21NO
Canonical SMILES	C1CN(CCC1(C2=CC=CC=C2)O)CC3=CC=CC=C3
InChI	1S/C18H21NO/c20-18(17-9-5-2-6-10-17)11-13-19(14-12-18)15-16-7-3-1-4-8-16/h1-10,20H,11-15H2
InChIKey	FCLMXEAPEVBCKQ-UHFFFAOYSA-N
PubChem Compound ID	97333
Target and Pathway
Target(s)	Nociceptin receptor	Target Info	Inhibitor	[528785]
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Peptide ligand-binding receptors
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528785	Bioorg Med Chem Lett. 2007 Jun 1;17(11):3023-7. Epub 2007 Mar 23.Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1.
Ref 528785	Bioorg Med Chem Lett. 2007 Jun 1;17(11):3023-7. Epub 2007 Mar 23.Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1.

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