Drug Information

Drug General Information
Drug ID
D0TZ1G
Former ID
DAP000296
Drug Name
Procaine
Synonyms
Allocaine; Anticort; Anuject; Duracaine; Gerokit; Gerovital; Jenacain; Jenacaine; Nissocaine; Norocaine; Novocain; Novocaine; Procain; Procaina; Procainum; Scurocaine; Spinocaine; Solution of novocain; Factor H3; SP01; SP01A; Stoff H3; Vitamin H3; Anticort (TM); Diethylaminoethyl p-aminobenzoate; Gerovital H-3; Novocain (TN); P-Aminobenzoyldiethylaminoethanol; P-Aminobenzyoyldiethylaminoethanol; Procaina [INN-Spanish]; Procaine (INN); Procaine [INN:BAN]; Procaine, base; Procainum [INN-Latin]; SP-01A; Solution of novocain (TN); Beta-Diethylaminoethyl 4-aminobenzoate; P-Aminobenzoic acid 2-diethylaminoethyl ester; Beta-(Diethylamino)ethyl 4-aminobenzoate; Beta-(Diethylamino)ethyl p-aminobenzoate; BENZOIC ACID,4-AMINO,2-DIETHYLAMINOETHYL ESTER PROCAIN BASE; Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester; Benzoic acid, p-amino-, 2-(diethylamino)ethyl ester; 2-(Diethylamino)ethyl 4-aminobenzoate; 2-(Diethylamino)ethyl p-aminobenzoate; 2-(Diethylamino)ethyl-4-aminobenzoate; 2-Diethylaminoethyl 4-aminobenzoate; 2-Diethylaminoethyl p-aminobenzoate; 2-Diethylaminoethylester kyseliny p-aminobenzoove; 2-Diethylaminoethylester kyseliny p-aminobenzoove [Czech]; 4-Aminobenzoesaeure-beta-diethylaminoethylester; 4-Aminobenzoic acid 2-(diethylamino) ethyl ester; 4-Aminobenzoic acid diethylaminoethyl ester
Drug Type
Small molecular drug
Indication Local anaesthetic [ICD10:R20.0] Approved [551871]
Therapeutic Class
Anesthetics
Company
Wyeth Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C13H20N2O2
InChI
InChI=1S/C13H20N2O2/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11/h5-8H,3-4,9-10,14H2,1-2H3
InChIKey
MFDFERRIHVXMIY-UHFFFAOYSA-N
CAS Number
CAS 59-46-1
PubChem Compound ID
4914
PubChem Substance ID
9579, 442275, 588149, 608576, 3138734, 5227621, 7980388, 8153025, 10528809, 11111696, 11111697, 11335295, 11360534, 11363732, 11366294, 11368856, 11371831, 11374114, 11377018, 11461506, 11466069, 11467189, 11485067, 11485818, 11489112, 11490372, 11492303, 11494652, 15196329, 29223992, 46507724, 47216639, 47440106, 47440107, 47588846, 48034960, 48259069, 48259070, 48259071, 49698882, 49885723, 50111197, 50612848, 53790362, 57304817, 57322521, 57820310, 85088908, 85788823, 90341175
ChEBI ID
ChEBI:8430
SuperDrug ATC ID
C05AD05; N01BA02; S01HA05
SuperDrug CAS ID
cas=000059461
Target and Pathway
Target(s) 5-hydroxytryptamine receptor 3A Target Info Antagonist [536543]
KEGG Pathway Serotonergic synapse
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway 5HT3 type receptor mediated signaling pathway
Reactome Ligand-gated ion channel transport
WikiPathways SIDS Susceptibility Pathways
Iron uptake and transport
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536543Local anesthetics have different mechanisms and sites of action at recombinant 5-HT3 receptors. Reg Anesth Pain Med. 2007 Nov-Dec;32(6):462-70.

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