Drug General Information
Drug ID	D0U2YL
Drug Name	CGS-23885
Synonyms	134822-78-9; CGS-23885
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[1560179]
Structure		Download 2D MOL 3D MOL
Formula	C17H16N2O4
PubChem Compound ID	131820
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Modulator
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 1560179	Inhibition of LTB4 biosynthesis in situ by CGS 23885, a potent 5-lipoxygenase inhibitor, correlates with its pleural fluid concentrations in an experimentally induced rat pleurisy model.

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