TTD | Drug: D0U4TN

Drug General Information
Drug ID	D0U4TN
Former ID	DNC007986
Drug Name	2-(2-hexylphenyl)isoindoline-1,3-dione
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529375]
Structure		Download 2D MOL 3D MOL
Formula	C20H21NO2
Canonical SMILES	CCCCCCC1=CC=CC=C1N2C(=O)C3=CC=CC=C3C2=O
InChI	1S/C20H21NO2/c1-2-3-4-5-10-15-11-6-9-14-18(15)21-19(22)16-12-7-8-13-17(16)20(21)23/h6-9,11-14H,2-5,10H2,1H3
InChIKey	USXHUJLIZBGCGH-UHFFFAOYSA-N
PubChem Compound ID	10638446
Target and Pathway
Target(s)	Oxysterols receptor LXR-alpha	Target Info	Inhibitor	[529375]
KEGG Pathway	PPAR signaling pathway
	Non-alcoholic fatty liver disease (NAFLD)
	Hepatitis C
Pathway Interaction Database	RXR and RAR heterodimerization with other nuclear receptor
WikiPathways	Nuclear Receptors in Lipid Metabolism and Toxicity
	Nuclear Receptors Meta-Pathway
	PPAR Alpha Pathway
	Liver X Receptor Pathway
	Adipogenesis
	SREBF and miR33 in cholesterol and lipid homeostasis
	Nuclear Receptors
References
Ref 529375	Bioorg Med Chem. 2008 Apr 15;16(8):4272-85. Epub 2008 Feb 29.Co-existence of alpha-glucosidase-inhibitory and liver X receptor-regulatory activities and their separation by structural development.
Ref 529375	Bioorg Med Chem. 2008 Apr 15;16(8):4272-85. Epub 2008 Feb 29.Co-existence of alpha-glucosidase-inhibitory and liver X receptor-regulatory activities and their separation by structural development.

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Drug Information