Drug General Information
Drug ID	D0U5PR
Former ID	DIB011241
Drug Name	Seridopidine
Synonyms	ACR-343
Drug Type	Small molecular drug
Indication	Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89]		Terminated	[546992]
Company	A Carlsson Research AB
Structure		Download 2D MOL 3D MOL
Formula	C14H20FNO2S
Canonical SMILES	c1c(cc(cc1S(=O)(=O)C)C1CCN(CC1)CC)F
CAS Number	CAS 883631-51-4
PubChem Compound ID	11572784
Target and Pathway
Target(s)	Sodium-dependent dopamine transporter	Target Info	Modulator	[533284]
KEGG Pathway	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Alcoholism
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	Parkinson disease
	Dopamine receptor mediated signaling pathway
Pathway Interaction Database	Alpha-synuclein signaling
Reactome	Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Dopaminergic Neurogenesis
	Parkinsons Disease Pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
	Neurotransmitter Clearance In The Synaptic Cleft
References
Ref 546992	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011877)
Ref 533284	Pridopidine selectively occupies sigma-1 rather than dopamine D2 receptors at behaviorally active doses. Psychopharmacology (Berl). 2015 Sep;232(18):3443-53.

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