Drug General Information
Drug ID	D0U6AL
Former ID	DIB013547
Drug Name	BI-L-357
Synonyms	BI-L-226
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Terminated	[545110]
Company	Boehringer Ingelheim Corp
Structure		Download 2D MOL 3D MOL
Formula	C18H18O4S
Canonical SMILES	c1(c(cc(/C=C/c2sccc2)cc1C)C)OC(=O)CCC(=O)O
CAS Number	CAS 149539-02-6
PubChem Compound ID	6440014
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Inhibitor	[534012]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 545110	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002162)
Ref 534012	A prodrug of a 2,6-disubstituted 4-(2-arylethenyl)phenol is a selective and orally active 5-lipoxygenase inhibitor. J Pharmacol Exp Ther. 1993 May;265(2):483-9.

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