Drug General Information
Drug ID
D0U9NY
Former ID
DAP001436
Drug Name
Ultracet
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Approved [536242]
Therapeutic Class
Analgesics
Structure
Download
2D MOL

3D MOL

Formula
C8H9NO2
Canonical SMILES
CC(=O)NC1=CC=C(C=C1)O
InChIKey
RZVAJINKPMORJF-UHFFFAOYSA-N
CAS Number
CAS 147630-09-9
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Inhibitor [537457]
Sodium-dependent serotonin transporter Target Info Inhibitor [537457]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 536242The Diversion of Ultram, Ultracet, and generic tramadol HCL. J Addict Dis. 2006;25(2):53-8.
Ref 537457Augmentation effect of combination therapy of aripiprazole and antidepressants on forced swimming test in mice. Psychopharmacology (Berl). 2009 Jun 11.

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