Drug General Information
Drug ID	D0UU5O
Former ID	DIB001821
Drug Name	5-HT 2c receptor agonists (obesity/schizophrenia), Galenea
Synonyms	5-HT 2c receptor agonists (obesity), Organix/Galenea
Indication	Obesity [ICD9: 278; ICD10:E66]		Investigative	[543963]
Company	Organix Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1c(cc2n(cc(c2c1O)CCN(C)C)CC)F
Target and Pathway
Target(s)	5-hydroxytryptamine 2C receptor	Target Info	Agonist	[543963]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543963	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 8).
Ref 543963	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 8).

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