Drug Information

Drug General Information
Drug ID
D0UV9F
Former ID
DIB008580
Drug Name
GSK-894281
Synonyms
GSK-894281; Ghrelin agonists (gastric motility disorder); SB-791016; Ghrelin agonists (gastric motility disorder), GlaxoSmithKline; Ghrelin agonists (gastric motility disorders), GSK
Drug Type
Small molecular drug
Indication Gastric motility disorder [ICD10:K22.4] Investigative [543633]
Company
GlaxoSmithKline plc
Structure
Download
2D MOL

3D MOL
Formula
C24H28FN3O4S
Canonical SMILES
Cc1oc(cc1)c1ccc(S(=O)(=O)N2[C@@H](CCC2)C(=O)N2C[C@H](N)<br />CC2)cc1F
PubChem Compound ID
24803511
Target and Pathway
Target(s) Growth hormone secretagogue receptor type 1 Target Info Agonist [543633]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway Leptin Signaling Pathway
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543633(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 246).
Ref 543633(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 246).

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