Drug Information

Drug General Information
Drug ID
D0V1IM
Former ID
DNC003641
Drug Name
L-791943
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526342]
Structure
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2D MOL

3D MOL
Formula
C24H17F10NO4
Canonical SMILES
C1=CC(=CC=C1C(CC2=CC=[N+](C=C2)[O-])C3=CC(=C(C=C3)OC(F)<br />F)OC(F)F)C(C(F)(F)F)(C(F)(F)F)O
InChI
1S/C24H17F10NO4/c25-20(26)38-18-6-3-15(12-19(18)39-21(27)28)17(11-13-7-9-35(37)10-8-13)14-1-4-16(5-2-14)22(36,23(29,30)31)24(32,33)34/h1-10,12,17,20-21,36H,11H2
InChIKey
VIOWRSXFEPSZFI-UHFFFAOYSA-N
PubChem Compound ID
9808191
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [526342]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addiction
Reactome DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
References
Ref 526342Bioorg Med Chem Lett. 2002 Jun 3;12(11):1457-61.Discovery of L-791,943: a potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor.
Ref 526342Bioorg Med Chem Lett. 2002 Jun 3;12(11):1457-61.Discovery of L-791,943: a potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor.

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