Drug General Information
Drug ID	D0V7HD
Former ID	DIB007860
Drug Name	BN-50726
Drug Type	Small molecular drug
Indication	Nerve injury [ICD10:T14.4]		Terminated	[544993]
Company	Ipsen
Structure		Download 2D MOL 3D MOL
Formula	C34H48ClN5O2S2
Canonical SMILES	c12c(C(=NCc3n1c(nn3)C)c1c(Cl)cccc1)c1c(s2)CN(S(=O)(=O)C<br />CCCCCCCCCCCCCCC)CC1
CAS Number	CAS 127279-06-5
PubChem Compound ID	164238
Target and Pathway
Target(s)	Platelet-activating factor receptor	Target Info	Antagonist	[526932]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Staphylococcus aureus infection
NetPath Pathway	IL5 Signaling Pathway
	Leptin Signaling Pathway
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (q) signalling events
	Interferon gamma signaling
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Interferon gamma signaling
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 544993	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001821)
Ref 526932	Effects of the PAF antagonists BN50726 and BN50739 on arrhythmogenesis and extent of necrosis during myocardial ischaemia/reperfusion in rabbits. Br J Pharmacol. 1992 Nov;107(3):705-9.

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