Drug General Information
Drug ID
D0V7XF
Former ID
DNAP001469
Drug Name
Dopexamine
Synonyms
Dopacard (TN)
Drug Type
Small molecular drug
Indication Cardiac failure [ICD10:I50] Approved [551871]
Structure
Download
2D MOL

3D MOL

Formula
C22H32N2O2
Canonical SMILES
C1=CC=C(C=C1)CCNCCCCCCNCCC2=CC(=C(C=C2)O)O
InChI
1S/C22H32N2O2/c25-21-11-10-20(18-22(21)26)13-17-24-15-7-2-1-6-14-23-16-12-19-8-4-3-5-9-19/h3-5,8-11,18,23-26H,1-2,6-7,12-17H2
InChIKey
RYBJORHCUPVNMB-UHFFFAOYSA-N
CAS Number
CAS 86197-47-9
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
C01CA14
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Modulator [536361]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.