Drug General Information
Drug ID
D0V8DB
Former ID
DNC004387
Drug Name
8-(3-Azido-phenyl)-6-iodo-quinoline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525895]
Structure
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2D MOL

3D MOL

Formula
C15H9IN4
Canonical SMILES
C1=CC(=CC(=C1)N=[N+]=[N-])C2=C3C(=CC(=C2)I)C=CC=N3
InChI
1S/C15H9IN4/c16-12-7-11-4-2-6-18-15(11)14(9-12)10-3-1-5-13(8-10)19-20-17/h1-9H
InChIKey
PBIQIEZSLAPKDM-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [525895]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addiction
Reactome DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
References
Ref 525895J Med Chem. 2000 Oct 19;43(21):3820-3.Hunting the emesis and efficacy targets of PDE4 inhibitors: identification of the photoaffinity probe 8-(3-azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ).
Ref 525895J Med Chem. 2000 Oct 19;43(21):3820-3.Hunting the emesis and efficacy targets of PDE4 inhibitors: identification of the photoaffinity probe 8-(3-azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ).

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