Drug General Information
Drug ID
D0VF6F
Former ID
DNC007297
Drug Name
N-(3-phenoxypyridin-4-yl)methanesulfonamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530415]
Structure
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2D MOL

3D MOL

Formula
C12H12N2O3S
Canonical SMILES
CS(=O)(=O)NC1=C(C=NC=C1)OC2=CC=CC=C2
InChI
1S/C12H12N2O3S/c1-18(15,16)14-11-7-8-13-9-12(11)17-10-5-3-2-4-6-10/h2-9H,1H3,(H,13,14)
InChIKey
CQEDUEBRINEBGP-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Prostaglandin G/H synthase 1 Target Info Inhibitor [530415]
BioCyc Pathway C20 prostanoid biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Platelet activation
Serotonergic synapse
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Prostaglandin Synthesis and Regulation
Arachidonic acid metabolism
Phase 1 - Functionalization of compounds
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 530415J Med Chem. 2009 Oct 8;52(19):5864-71.Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors.
Ref 530415J Med Chem. 2009 Oct 8;52(19):5864-71.Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors.

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