Drug General Information
Drug ID	D0VN7G
Former ID	DNC005009
Drug Name	Hexahydro-pyrrolizin-(3E)-ylideneamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527210]
Structure		Download 2D MOL 3D MOL
Formula	C7H12N2
Canonical SMILES	C1CC2CCC(=N)N2C1
InChI	1S/C7H12N2/c8-7-4-3-6-2-1-5-9(6)7/h6,8H,1-5H2
InChIKey	IGTGCXXJCCYMRS-UHFFFAOYSA-N
PubChem Compound ID	44393480
Target and Pathway
Target(s)	Nitric-oxide synthase, brain	Target Info	Inhibitor	[527210]
BioCyc Pathway	Citrulline-nitric oxide cycle
KEGG Pathway	Arginine and proline metabolism
	Metabolic pathways
	Calcium signaling pathway
	Phagosome
	Circadian entrainment
	Long-term depression
	Salivary secretion
	Alzheimer's disease
	Amyotrophic lateral sclerosis (ALS)
NetPath Pathway	EGFR1 Signaling Pathway
PANTHER Pathway	CCKR signaling map ST
PathWhiz Pathway	Arginine and Proline Metabolism
Reactome	ROS production in response to bacteria
	Nitric oxide stimulates guanylate cyclase
WikiPathways	Monoamine Transport
	Myometrial Relaxation and Contraction Pathways
	Amyotrophic lateral sclerosis (ALS)
	Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
	Spinal Cord Injury
	Alzheimers Disease
	Effects of Nitric Oxide
	Serotonin Transporter Activity
References
Ref 527210	Bioorg Med Chem Lett. 2004 Sep 6;14(17):4539-44.Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase.
Ref 527210	Bioorg Med Chem Lett. 2004 Sep 6;14(17):4539-44.Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.