Drug General Information
Drug ID	D0W2HW
Former ID	DNC007095
Drug Name	N,N-diethyl-2-(1H-indol-3-yl)ethanamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528416]
Structure		Download 2D MOL 3D MOL
Formula	C14H20N2
Canonical SMILES	CCN(CC)CCC1=CNC2=CC=CC=C21
InChI	1S/C14H20N2/c1-3-16(4-2)10-9-12-11-15-14-8-6-5-7-13(12)14/h5-8,11,15H,3-4,9-10H2,1-2H3
InChIKey	LSSUMOWDTKZHHT-UHFFFAOYSA-N
CAS Number	CAS 61-51-8
PubChem Compound ID	6090
Target and Pathway
Target(s)	5-hydroxytryptamine 6 receptor	Target Info	Inhibitor	[528416]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528416	Bioorg Med Chem Lett. 2006 Nov 15;16(22):5832-5. Epub 2006 Aug 30.Interaction of N1-unsubstituted and N1-benzenesulfonyltryptamines at h5-HT6 receptors.
Ref 528416	Bioorg Med Chem Lett. 2006 Nov 15;16(22):5832-5. Epub 2006 Aug 30.Interaction of N1-unsubstituted and N1-benzenesulfonyltryptamines at h5-HT6 receptors.

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