Drug General Information
Drug ID	D0W8EP
Drug Name	SDZ-205-557
Synonyms	137196-67-9; SDZ-205-557
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[1560033]
Structure		Download 2D MOL 3D MOL
Formula	C14H21ClN2O3
PubChem Compound ID	5191
Target and Pathway
Target(s)	5-hydroxytryptamine 4 receptor	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	5HT4 type receptor mediated signaling pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 1560033	SDZ 205-557, a selective antagonist at 5-HT4 receptors in the isolated guinea pig ileum.

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