Drug General Information
Drug ID	D0W9PG
Former ID	DIB016590
Drug Name	Pyrazinoylguanidine
Synonyms	PZG
Indication	Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1]		Discontinued in Phase 2	[545139]
Company	Sparta Pharmaceuticals Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	N(C(=O)c1nccnc1)C(=N)N
CAS Number	CAS 60398-24-5
Target and Pathway
Target(s)	Sodium channel	Target Info	Modulator	[528291]
KEGG Pathway	Dopaminergic synapse
Reactome	Interaction between L1 and Ankyrins
References
Ref 545139	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002279)
Ref 528291	Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis. J Med Chem. 2006 Jul 13;49(14):4098-115.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.