Drug General Information
Drug ID
D0X2AT
Former ID
DIB012018
Drug Name
Rhopressa
Indication Glaucoma [ICD9: 365; ICD10:H40-H42] Phase 2 [533091]
Company
Aerie pharmaceuticals
Structure
Download
2D MOL

3D MOL

Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Modulator [533091]
Rho associated protein kinase Target Info Modulator [533091]
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 533091Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.
Ref 533091Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.

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