Drug General Information
Drug ID	D0X4LQ
Former ID	DNC001617
Drug Name	3-MeSO2-DDE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[535383]
Structure		Download 2D MOL 3D MOL
Formula	C15H10Cl4O2S
Canonical SMILES	CS(=O)(=O)C1=C(C=CC(=C1)Cl)C(=C(Cl)Cl)C2=CC=C(C=C2)Cl
InChI	1S/C15H10Cl4O2S/c1-22(20,21)13-8-11(17)6-7-12(13)14(15(18)19)9-2-4-10(16)5-3-9/h2-8H,1H3
InChIKey	YQCQEXWXRQQMAR-UHFFFAOYSA-N
PubChem Compound ID	119115
PubChem Substance ID	10238350, 29300075, 46503888, 50906494, 57339335, 103144572, 104407579, 117466633, 125671084, 129831957, 135074601, 144087501, 162633600
Target and Pathway
Target(s)	Cytochrome P450 11B1, mitochondrial	Target Info	Inhibitor	[535383]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Glucocorticoid biosynthesis
	Mineralocorticoid biosynthesis
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
PathWhiz Pathway	Steroidogenesis
Reactome	Glucocorticoid biosynthesis
	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Oxidation by Cytochrome P450
	Metabolism of steroid hormones and vitamin D
	Corticotropin-releasing hormone
References
Ref 535383	Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. Toxicol In Vitro. 2002 Apr;16(2):113-21.
Ref 535383	Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. Toxicol In Vitro. 2002 Apr;16(2):113-21.

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