Drug Information

Drug General Information
Drug ID
D0X4NX
Former ID
DNC001140
Drug Name
Polyporic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534955]
Structure
Download
2D MOL

3D MOL
Formula
C18H12O4
Canonical SMILES
C1=CC=C(C=C1)C2=C(C(=O)C(=C(C2=O)O)C3=CC=CC=C3)O
InChI
1S/C18H12O4/c19-15-13(11-7-3-1-4-8-11)16(20)18(22)14(17(15)21)12-9-5-2-6-10-12/h1-10,19,22H
InChIKey
HZKFHDXTSAYOSN-UHFFFAOYSA-N
PubChem Compound ID
11056
PubChem Substance ID
98392, 605348, 5082610, 8138243, 8158049, 15468067, 29279400, 49890287, 50491390, 57326657, 103617129, 104325010, 134340132, 134340375, 134977818, 162547832, 180386877, 228556051, 241094657, 250113854
SuperDrug ATC ID
A02BC05
SuperDrug CAS ID
cas=161973100
Target and Pathway
Target(s) Dihydroorotate dehydrogenase, mitochondrial Target Info Inhibitor [534955]
KEGG Pathway Pyrimidine metabolism
Metabolic pathways
PathWhiz Pathway Pyrimidine Metabolism
Reactome Pyrimidine biosynthesis
WikiPathways Metabolism of nucleotides
References
Ref 534955Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid. Chem Biol Interact. 2000 Jan 3;124(1):61-76.
Ref 534955Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid. Chem Biol Interact. 2000 Jan 3;124(1):61-76.

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