Drug Information

Drug General Information
Drug ID
D0X5SJ
Former ID
DNAP001482
Drug Name
Alacepril
Synonyms
Cetapril (TN)
Drug Type
Small molecular drug
Indication Cardiovascular disorder [ICD10:I00-I99] Approved [551871]
Company
Dainippon
Structure
Download
2D MOL

3D MOL
Formula
C20H26N2O5S
Canonical SMILES
CC(CSC(=O)C)C(=O)N1CCCC1C(=O)NC(CC2=CC=CC=C2)C(=O)O
InChI
1S/C20H26N2O5S/c1-13(12-28-14(2)23)19(25)22-10-6-9-17(22)18(24)21-16(20(26)27)11-15-7-4-3-5-8-15/h3-5,7-8,13,16-17H,6,9-12H2,1-2H3,(H,21,24)(H,26,27)/t13-,16+,17+/m1/s1
InChIKey
FHHHOYXPRDYHEZ-COXVUDFISA-N
CAS Number
CAS 74258-86-9
PubChem Compound ID
71992
PubChem Substance ID
7848962, 8194954, 12012862, 15451107, 43128232, 50006743, 50442755, 57318468, 99031293, 103095512, 103157165, 104351820, 117570221, 119525747, 124772209, 124893756, 127327732, 127327733, 127327734, 127327735, 127327736, 127847193, 135029396, 135377129, 137189513, 137231960, 141323946, 144206457, 152056074, 160697856, 163693475, 164814629, 179151063, 184545374, 187072450, 198968997, 223554738, 223914456, 226421005, 241134090, 252214694, 252359200
Target and Pathway
Target(s) Angiotensin-converting enzyme Target Info Modulator [534314], [536361]
KEGG Pathway Renin-angiotensin system
Chagas disease (American trypanosomiasis)
Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 534314Natural products in drug discovery and development. J Nat Prod. 1997 Jan;60(1):52-60.
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.