Drug Information

Drug General Information
Drug ID
D0X5ZO
Former ID
DCL001121
Drug Name
SSR-162369
Drug Type
Small molecular drug
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Discontinued in Phase 1 [548129]
Company
Sanofi-Aventis
Structure
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2D MOL

3D MOL
Formula
C27H33N5O2
Canonical SMILES
CC(=CCN1C(=NC2=C1C(=O)N(C(=C)N2C)CC(=O)C3=CC=CC=C3)C4CC<br />C5C4CCN5)C
InChI
1S/C27H33N5O2/c1-17(2)13-15-31-24-26(29-25(31)21-10-11-22-20(21)12-14-28-22)30(4)18(3)32(27(24)34)16-23(33)19-8-6-5-7-9-19/h5-9,13,20-22,28H,3,10-12,14-16H2,1-2,4H3/t20-,21?,22+/m0/s1
InChIKey
PBLJWGCWKPKYPH-JAFNVKOHSA-N
PubChem Compound ID
56603733
PubChem Substance ID
134339488
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Inhibitor [537022]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 548129Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022199)
Ref 537022Emerging drug candidates of dipeptidyl peptidase IV (DPP IV) inhibitor class for the treatment of Type 2 Diabetes. Curr Drug Targets. 2009 Jan;10(1):71-87.

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