Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0X7HD
|
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| Former ID |
DNC010280
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| Drug Name |
CP-810123
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [530609] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C14H18N4O
|
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| Canonical SMILES |
CC1=NC2=C(C=C1)OC(=N2)N3CCN4CCC3CC4
|
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| InChI |
1S/C14H18N4O/c1-10-2-3-12-13(15-10)16-14(19-12)18-9-8-17-6-4-11(18)5-7-17/h2-3,11H,4-9H2,1H3
|
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| InChIKey |
BSNKYWSMUAGMDO-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Neuronal acetylcholine receptor protein, alpha-7 chain | Target Info | Inhibitor | [530609] | |
| 5-hydroxytryptamine receptor 3A | Target Info | Inhibitor | [530609] | ||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| References | |||||
| Ref 530609 | J Med Chem. 2010 Feb 11;53(3):1222-37.Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models. | ||||
| Ref 530609 | J Med Chem. 2010 Feb 11;53(3):1222-37.Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models. | ||||
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