Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0X8BU
|
||||
| Former ID |
DIB019337
|
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| Drug Name |
compound 20
|
||||
| Synonyms |
PCM126
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [532265] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C35H50N2O4
|
||||
| InChI |
InChI=1S/C35H50N2O4/c1-21(8-13-32(39)37-31(33(40)41)18-22-20-36-30-7-5-4-6-25(22)30)27-11-12-28-26-10-9-23-19-24(38)14-16-34(23,2)29(26)15-17-35(27,28)3/h4-7,20-21,23-24,26-29,31,36,38H,8-19H2,1-3H3,(H,37,39)(H,40,41)/t21-,23-,24-,26+,27-,28+,29+,31+,34+,35-/m1/s1
|
||||
| InChIKey |
ITOFPJRDSCGOSA-KZLRUDJFSA-N
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Ephrin type-A receptor 2 | Target Info | Inhibitor | [532265] | |
| EPH receptor B6 | Target Info | Inhibitor | [532265] | ||
| EPH receptor A8 | Target Info | Inhibitor | [532265] | ||
| EPH receptor A1 | Target Info | Inhibitor | [532265] | ||
| EPH receptor A6 | Target Info | Inhibitor | [532265] | ||
| EPH receptor A5 | Target Info | Inhibitor | [532265] | ||
| Ephrin type-B receptor 4 | Target Info | Inhibitor | [532265] | ||
| Epha3 tyrosine kinase receptor | Target Info | Inhibitor | [532265] | ||
| Epha4 tyrosine kinase receptor | Target Info | Inhibitor | [532265] | ||
| EPH receptor B3 | Target Info | Inhibitor | [532265] | ||
| EPH receptor A7 | Target Info | Inhibitor | [532265] | ||
| EPH receptor B1 | Target Info | Inhibitor | [532265] | ||
| Ephrin type-B receptor 2 | Target Info | Inhibitor | [532265] | ||
| PANTHER Pathway | Angiogenesis | ||||
| Pathway Interaction Database | EphrinA-EPHA pathway | ||||
| Arf6 signaling events | |||||
| Direct p53 effectors | |||||
| EPHA forward signaling | |||||
| Stabilization and expansion of the E-cadherin adherens junction | |||||
| EPHA2 forward signalingephbfwdpathway:EPHB forward signaling | |||||
| EphrinB-EPHB pathway | |||||
| Ephrin B reverse signalingephrina_ephapathway:EphrinA-EPHA pathway | |||||
| EPHA forward signalingephrina_ephapathway:EphrinA-EPHA pathway | |||||
| EPHA forward signalingephbfwdpathway:EPHB forward signaling | |||||
| Syndecan-2-mediated signaling events | |||||
| Ephrin B reverse signaling | |||||
| References | |||||
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