Drug Information

Drug General Information
Drug ID
D0X8DW
Former ID
DNC011419
Drug Name
6-Nitro-4-phenyl-2-piperazin-1-yl-quinoline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526278]
Structure
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2D MOL

3D MOL
Formula
C19H18N4O2
Canonical SMILES
C1CN(CCN1)C2=NC3=C(C=C(C=C3)[N+](=O)[O-])C(=C2)C4=CC=CC<br />=C4
InChI
1S/C19H18N4O2/c24-23(25)15-6-7-18-17(12-15)16(14-4-2-1-3-5-14)13-19(21-18)22-10-8-20-9-11-22/h1-7,12-13,20H,8-11H2
InChIKey
VABDCPDEFUPFHF-UHFFFAOYSA-N
PubChem Compound ID
44379683
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Inhibitor [526278]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 526278Bioorg Med Chem Lett. 2002 Mar 11;12(5):811-5.Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 2: 4-substituted 6-nitroquipazines.
Ref 526278Bioorg Med Chem Lett. 2002 Mar 11;12(5):811-5.Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 2: 4-substituted 6-nitroquipazines.

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