Drug Information

Drug General Information
Drug ID
D0Y2XY
Former ID
DIB018467
Drug Name
12R-HETE
Synonyms
12r-HETE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540352]
Structure
Download
2D MOL
Formula
C20H32O3
InChI
InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m1/s1
InChIKey
ZNHVWPKMFKADKW-ZYBDYUKJSA-N
PubChem Compound ID
5283156
PubChem Substance ID
801685, 4266114, 11038790, 14718421, 14752679, 14850506, 17395820, 26754747, 26754748, 39316570, 47217014, 48334746, 50110768, 57358869, 77183169, 92309713, 99300627, 99302145, 104046389, 113859253, 131277740, 135651371, 164757739, 179205503, 227683593, 241163503, 250132978, 252378533, 252455437, 252463821
Target and Pathway
Target(s) Leukotriene B4 receptor 2 Target Info Agonist [534395]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Reactome Leukotriene receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540352(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3405).
Ref 534395A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature. 1997 Jun 5;387(6633):620-4.

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