Drug General Information
Drug ID	D0Y5QO
Former ID	DIB012490
Drug Name	GK-128
Indication	Emesis [ICD9: 787; ICD10:R11]		Terminated	[545075]
Company	Taisho Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1(c(=O)c2c3c(ccc2sc1)cccc3)Cn1c(ncc1)C.Cl
CAS Number	CAS 139958-03-5
Target and Pathway
Target(s)	5-Hydroxytryptamine 3 receptor	Target Info	Modulator	[534513]
References
Ref 545075	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002051)
Ref 534513	Effect of a novel 5-hydroxytryptamine3 (5-HT3) receptor antagonist, GK-128, on 5-HT3 receptors mediating contractions and relaxations in guinea-pig distal colon. Gen Pharmacol. 1997 Sep;29(3):353-9.

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