Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Y6SN
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| Former ID |
DCL000976
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| Drug Name |
SB-277011
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| Synonyms |
SB 277011; SB 277011A; SB 277011-A; N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide
|
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| Drug Type |
Small molecular drug
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| Company |
GlaxoSmithKline
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| Structure |
|
Download2D MOL |
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| Formula |
C28H30N4O
|
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| InChI |
InChI=1S/C28H30N4O/c29-18-21-5-8-23-19-32(16-13-22(23)17-21)15-12-20-6-9-24(10-7-20)31-28(33)26-11-14-30-27-4-2-1-3-25(26)27/h1-5,8,11,14,17,20,24H,6-7,9-10,12-13,15-16,19H2,(H,31,33)/t20-,24-
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| InChIKey |
OLWRVVHPJFLNPW-LSNLESRRSA-N
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| CAS Number |
CAS 304853-42-7
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7979281, 14759237, 39340816, 47731229, 48329042, 50075888, 56210210, 57359353, 77302121, 85209431, 103291265, 103857948, 104053095, 104133783, 114155250, 125329835, 125647247, 128827839, 128827840, 131305404, 134222959, 135323990, 135651003, 137144216, 152043734, 152258270, 160647107, 160849674, 162011819, 164233548, 164764956, 170485706, 174528353, 179293940, 186014801, 229146917, 229146923, 251963242, 252670316
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| Target and Pathway | |||||
| Target(s) | D(3) dopamine receptor | Target Info | Antagonist | [536463] | |
| References | |||||
| Ref 536463 | The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31. | ||||
| Ref 538907 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 143). | ||||
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