Drug Information

Drug General Information
Drug ID
D0Y8KY
Former ID
DIB020848
Drug Name
RP73870
Synonyms
RP 73870
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540458]
Structure
Download
2D MOL
Formula
C27H30N4O7S
InChI
InChI=1S/C27H30N4O7S/c1-30(22-10-4-3-5-11-22)26(33)19-31(23-12-7-13-24(17-23)38-2)25(32)18-28-27(34)29-21-9-6-8-20(16-21)14-15-39(35,36)37/h3-13,16-17H,14-15,18-19H2,1-2H3,(H2,28,29,34)(H,35,36,37)
InChIKey
NGZMTMPEGDUWJQ-UHFFFAOYSA-N
PubChem Compound ID
5311414
PubChem Substance ID
7980541, 11056488, 14910721, 39341092, 52196438, 57359470, 85209269, 114156031, 178100503
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info Antagonist [525523]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPK
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540458(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3523).
Ref 525523Pharmacological analysis of CCK2 receptor antagonists using isolated rat stomach ECL cells. Br J Pharmacol. 1999 May;127(2):530-6.

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