Drug General Information
Drug ID	D0Y8ZN
Former ID	DCL000582
Drug Name	Ofatumumab
Synonyms	Arzerra (TN)
Drug Type	Antibody
Indication	Chronic lymphocytic leukaemia [ICD10:C91]		Approved	[530677], [541858]
	Diffuse large B-cell lymphoma; Multiple sclerosis [ICD9: 202.8, 340; ICD10:C85.1, G35]		Phase 3	[530677], [541858]
	Rheumatold arthritis; Follicular lymphoma [ICD9: 202.0, 714; ICD10:C82, M05-M06]		Phase 2	[530677], [541858]
Company	GlaxoSmithKline
Structure		Download 2D MOL 3D MOL
Formula	C12H10N4O2
PubChem Compound ID	6918251
SuperDrug ATC ID	L01XC10
Target and Pathway
Target(s)	B-lymphocyte antigen CD20	Target Info		[530677], [550963]
KEGG Pathway	Hematopoietic cell lineage
References
Ref 530677	Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
Ref 541858	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6778).
Ref 530677	Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
Ref 550963	Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).

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