Drug Information

Drug General Information
Drug ID
D0YQ8V
Former ID
DIB019602
Drug Name
compound 8
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532479]
Structure
Download
2D MOL
Formula
C24H21N3O3
InChI
InChI=1S/C24H21N3O3/c1-28-21-10-16(11-22(29-2)23(21)30-3)17-9-18-19(13-27-24(18)26-12-17)14-4-5-20-15(8-14)6-7-25-20/h4-13,25H,1-3H3,(H,26,27)
InChIKey
UQHKXSZPEUNUDH-UHFFFAOYSA-N
PubChem Compound ID
46236221
PubChem Substance ID
96096862, 120489667, 174519671, 175453889, 224571600, 227011499, 247270486, 249565875
Target and Pathway
Target(s) Mitogen-activated protein kinase kinase kinase 11 Target Info Inhibitor [532479]
KEGG Pathway MAPK signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
PANTHER Pathway CCKR signaling map ST
Pathway Interaction Database Reelin signaling pathway
CDC42 signaling events
IFN-gamma pathway
RAC1 signaling pathway
References
Ref 532479Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem. 2013 Oct 24;56(20):8032-48.
Ref 532479Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem. 2013 Oct 24;56(20):8032-48.

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