Drug Information

Drug General Information
Drug ID
D0YZ8I
Former ID
DNC000831
Drug Name
JWH-015
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540936]
Structure
Download
2D MOL

3D MOL
Formula
C23H21NO
InChI
InChI=1S/C23H21NO/c1-3-15-24-16(2)22(20-12-6-7-14-21(20)24)23(25)19-13-8-10-17-9-4-5-11-18(17)19/h4-14H,3,15H2,1-2H3
InChIKey
LJSBBBWQTLXQEN-UHFFFAOYSA-N
PubChem Compound ID
4273754
PubChem Substance ID
6274360, 9624193, 11114036, 14875077, 24278502, 49689354, 56463190, 57309607, 57356879, 71754794, 79509496, 85788648, 91746339, 103274236, 112818142, 124801407, 125335445, 128498955, 134339061, 134340148, 135260952, 135289033, 135368331, 135698395, 137103971, 142472542, 143494080, 152048721, 152237521, 162023061, 162249344, 164761410, 165238056, 170481101, 175608137, 178102197, 178126927, 179337480, 184597693, 198973429, 226812352, 241182343, 250120982, 252451159, 252457923
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Agonist [536731]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 540936(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5558).
Ref 536731Posttraining activation of CB1 cannabinoid receptors in the CA1 region of the dorsal hippocampus impairs object recognition long-term memory. Neurobiol Learn Mem. 2008 Sep;90(2):374-81. Epub 2008 Jun 3.

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