Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z2FB
|
||||
| Former ID |
DNC002879
|
||||
| Drug Name |
Piclamilast
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] | Phase 2 | [525937] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C18H18Cl2N2O3
|
||||
| Canonical SMILES |
COC1=C(C=C(C=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC3CCCC3
|
||||
| InChI |
1S/C18H18Cl2N2O3/c1-24-15-7-6-11(8-16(15)25-12-4-2-3-5-12)18(23)22-17-13(19)9-21-10-14(17)20/h6-10,12H,2-5H2,1H3,(H,21,22,23)
|
||||
| InChIKey |
RRRUXBQSQLKHEL-UHFFFAOYSA-N
|
||||
| CAS Number |
CAS 144035-83-6
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
3283043, 4850048, 7889890, 10252206, 12014798, 14780156, 46230676, 46393567, 46393576, 46508612, 46515100, 47207143, 48105224, 48105225, 48413504, 49876220, 57288808, 57309646, 57348019, 77180576, 91045369, 103222001, 104439116, 126442933, 129172131, 135258387, 137009719, 140119531, 144220535, 152198765, 160965019, 163144556, 163777440, 179149930, 198987688, 223442587, 225009593, 226414392, 241035753, 241377035, 250033411, 251903231, 251960644, 252158140, 252451290, 252455940
|
||||
| Target and Pathway | |||||
| Target(s) | CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [551373] | |
| Type IV phosphodiesterase | Target Info | Inhibitor | [551373] | ||
| CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [551373] | ||
| NetPath Pathway | IL5 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| PathWhiz Pathway | Purine Metabolism | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.