Drug Information

Drug General Information
Drug ID
D0Z2WQ
Former ID
DNC001183
Drug Name
Quinelorane
Drug Type
Small molecular drug
Indication Male sexual disorders [ICD10:F52] Discontinued in Phase 3 [543323], [544908]
Structure
Download
2D MOL

3D MOL
Formula
C14H22N4
InChI
InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m1/s1
InChIKey
TUFADSGTJUOBEH-ZWNOBZJWSA-N
CAS Number
CAS 97466-90-5
PubChem Compound ID
57242
PubChem Substance ID
8185128, 11111703, 14823336, 15196615, 43114956, 47349364, 47646566, 47795046, 48169381, 50035171, 51048994, 57309569, 85788352, 90341289, 103405082, 103927698, 104312139, 124750174, 124892377, 135014815, 135650871, 135696152, 135749149, 137036431, 141724360, 144205562, 162223515, 170466296, 179151490, 184547243, 198951792, 226709836
Target and Pathway
Target(s) D(3) dopamine receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
Dopaminergic synapse
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
GPCRs, Other
References
Ref 543323(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 954).
Ref 544908Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001472)

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