Drug Information

Drug General Information
Drug ID
D0Z4QC
Former ID
DIB003622
Drug Name
SDZ-SER-082
Drug Type
Small molecular drug
Indication Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] Terminated [539249], [546128]
Company
Novartis AG
Structure
Download
2D MOL

3D MOL
Formula
C15H20N2
InChI
InChI=1S/C15H20N2/c1-16-7-5-12-9-17-8-6-11-3-2-4-13(15(11)17)14(12)10-16/h2-4,12,14H,5-10H2,1H3/t12-,14-/m1/s1
InChIKey
YASBOGFWAMXINH-TZMCWYRMSA-N
CAS Number
CAS 141474-54-6
PubChem Compound ID
9859407
PubChem Substance ID
14822864, 15220629, 24152757, 45281702, 48331994, 48331995, 79484333, 85788314, 103305803, 135651035, 136351199, 136352573, 238076607
Target and Pathway
Target(s) 5-hydroxytryptamine 2C receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 539249(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 195).
Ref 546128Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006463)

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