Drug General Information
Drug ID	D0ZI0C
Former ID	DIB007781
Drug Name	Dersalazine
Synonyms	UR-12715; UR-12746
Drug Type	Small molecular drug
Indication	Inflammatory bowel disease [ICD9: 555, 556; ICD10:K50, K51]		Phase 2	[544223]
Company	Grupo Uriach
Structure		Download 2D MOL 3D MOL
Formula	C35H31N6NaO4
Canonical SMILES	n1(c(nc2c1ccnc2)C)CC1CCN(C(=O)/C=C(\c2ccc(/N=N/c3cc(C(=<br />O)O)c(cc3)O)cc2)/c2ccccc2)CC1
CAS Number	CAS 188913-58-8
PubChem Compound ID	57331752
Target and Pathway
Target(s)	Platelet-activating factor receptor	Target Info	Inhibitor	[544223]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Staphylococcus aureus infection
NetPath Pathway	IL5 Signaling Pathway
	Leptin Signaling Pathway
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (q) signalling events
	Interferon gamma signaling
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Interferon gamma signaling
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 544223	The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis. Br J Pharmacol. 2012 February; 165(3): 729-740.
Ref 544223	The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis. Br J Pharmacol. 2012 February; 165(3): 729-740.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.