Drug Information

Drug General Information
Drug ID
DX2HOZ
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-pyridin-3-yl-piperidine-1-carboxamidine
Synonyms
CHEMBL348576
Indication Discovery agent Investigative [1587926]
Formula
C26H22BrClN6
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/c4cccnc4)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C26H22BrClN6/c27-20-12-19-4-3-18-13-21(28)5-6-23(18)24(25(19)31-14-20)17-7-10-34(11-8-17)26(32-16-29)33-22-2-1-9-30-15-22/h1-2,5-6,9,12-15H,3-4,7-8,10-11H2,(H,32,33)
InChIKey
JUOFAUOWWKTUIO-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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