Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXW5BG
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| Drug Name |
1-((3,5-bis(trifluoromethyl)phenyl)(thiophen-2-yl)methylene)thiosemicarbazide
|
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| Synonyms |
CHEMBL260921
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C14H9F6N3S2
|
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| Canonical SMILES |
NC(=S)N\\N=C(\\c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/c2cccs2
|
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| InChI |
InChI=1S/C14H9F6N3S2/c15-13(16,17)8-4-7(5-9(6-8)14(18,19)20)11(22-23-12(21)24)10-2-1-3-25-10/h1-6H,(H3,21,23,24)/b22-11-
|
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| InChIKey |
LJSGOJMCGFKQHB-JJFYIABZSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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