Drug General Information
Drug ID
Drug Name
2-{4-[2-(1,2,3,4-Tetrahydro-quinolin-7-yloxy)-ethoxy]-benzyl}-malonic acid monomethyl ester
Indication Discovery agent Investigative [1587926]
Canonical SMILES
Target and Pathway
Target(s) Peroxisome proliferator activated receptor gamma Target Info [1587926]
Peroxisomeproliferator activated receptor delta Target Info [1587926]
KEGG Pathway PPAR signaling pathway
AMPK signaling pathway
Osteoclast differentiation
Huntington's disease
Pathways in cancer
Transcriptional misregulation in cancer
Thyroid cancerhsa03320:PPAR signaling pathway
Wnt signaling pathway
Acute myeloid leukemia
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Leptin Signaling PathwayNetPath_14:IL2 Signaling Pathway
PANTHER Pathway CCKR signaling map STP00057:Wnt signaling pathway
Pathway Interaction Database Noncanonical Wnt signaling pathway
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Signaling events mediated by HDAC Class I
RXR and RAR heterodimerization with other nuclear receptor
Regulation of retinoblastoma proteinps1pathway:Presenilin action in Notch and Wnt signaling
Reactome PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation
Nuclear Receptor transcription pathwayR-HSA-200425:Import of palmitoyl-CoA into the mitochondrial matrix
Regulation of pyruvate dehydrogenase (PDH) complex
Nuclear Receptor transcription pathway
WikiPathways Wnt Signaling Pathway Netpath
Nuclear Receptors in Lipid Metabolism and Toxicity
Differentiation of white and brown adipocyte
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Transcriptional Regulation of White Adipocyte Differentiation
SREBP signalling
Nuclear ReceptorsWP399:Wnt Signaling Pathway and Pluripotency
NRF2 pathway
Nuclear Receptors Meta-Pathway
Vitamin D Receptor Pathway
Ectoderm Differentiation
Nuclear Receptors
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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