Multi-target agents

Target Pair Drug Name
VEGFR2 --- TEK 4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide Drug Info
Ftase --- FPTase (2S)-methyl 2-(2-(3-(3-(1H-imidazol-5-yl)propyl)-5-methyl-5-(naphthalen-1-yl)-2,4-dioxoimidazolidin-1-yl)acetamido)-4-(methylthio)butanoate Drug Info
NPKCdelta --- NPKCtheta 2-(4-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitrile Drug Info
VEGFR2 --- TEK 19-methyl-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one Drug Info
Ftase --- FPTase 1-[(2R,3R)-6-Chloro-3-(5-chloro-thiophen-2-ylmethoxy)-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole Drug Info
NPKCdelta --- NPKCtheta 5-(5-((4-cyclopentylpiperazin-1-yl)methyl)furan-3-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile Drug Info
VEGFR2 --- TEK 1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea Drug Info
Ftase --- FPTase ethyl 2-(5-methyl-3-(3-(1-methyl-1H-imidazol-5-yl)propyl)-5-(naphthalen-1-yl)-2,4-dioxoimidazolidin-1-yl)acetate Drug Info
NPKCdelta --- NPKCtheta (R)-2-(3-(3-(dimethylamino)pyrrolidin-1-yl)-3-oxoprop-1-enyl)-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitrile Drug Info
VEGFR2 --- TEK SID124350139 Drug Info
Ftase --- FPTase 4-[1-Amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-{3-[1-methyl-2-oxo-3-(3,3,3-trifluoro-propyl)-azepan-3-yl]-phenoxy}-benzonitrile Drug Info
NPKCdelta --- NPKCtheta 5-(5-((2,3-dihydroxypropylamino)methyl)benzofuran-2-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile Drug Info
VEGFR2 --- VEGFR1 6-(4-Methoxy-phenyl)-3-pyridin-3-yl-pyrazolo[1,5-a]pyrimidine Drug Info
Ftase --- FPTase [1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-piperidin-1-yl-methanone Drug Info
NPKCdelta --- NPKCtheta 5-(5-((4-isopropylpiperazin-1-yl)methyl)furan-3-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile Drug Info
VEGFR2 --- VEGFR1 2-(pyridin-4-ylmethylamino)-N-(quinolin-3-yl)benzamide Drug Info
GSK --- VEGFR 4-amino-5-(4-(benzenesulfonylamino)-phenyl)-6-(3-pyridyl)-furo[2,3-d]pyrimidine Drug Info
EGFR3 --- HER2 N-[4-(3-Bromo-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-acrylamide Drug Info
NPKCdelta --- NPKCtheta 4-(1H-indol-4-ylamino)-5-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)nicotinonitrile Drug Info
VEGFR2 --- VEGFR1 N-(3,5-bis(trifluoromethyl)phenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-pyrazole-5-carboxamide Drug Info
H3 --- SERT 3-(3-bromophenoxy)-N,N-dimethyl-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)propan-1-amine Drug Info
EGFR3 --- HER2 {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid,(3S)-3-morpholinylmethyl ester Drug Info
PI3K gamma --- PI3K delta (3-(6-((4-(Methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)phenyl)methanol Drug Info
VEGFR2 --- VEGFR1 4-(2,4-Dichloro-benzoylsulfamoyl)-benzoic acid methyl ester Drug Info
H3 --- SERT 3-(4-fluorophenoxy)-N,N-dimethyl-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)propan-1-amine Drug Info
EGFR3 --- HER2 7-(4-(3-Ethynyl-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide Drug Info
PI3K gamma --- PI3K delta 2-(6-(1H-pyrazol-4-yl)-2H-benzo[b][1,4]oxazin-4(3H)-yl)-6,6-dimethyl-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one Drug Info
VEGFR2 --- VEGFR1 1-methyl-4-(pyridin-3-ylmethylamino)-N-(4-(trifluoromethyl)phenyl)-1H-imidazole-5-carboxamide Drug Info
H3 --- SERT 4-(4-chloro-3-fluorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine Drug Info
EGFR3 --- HER2 (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(naphthalen-1-yl)acrylate Drug Info
PI3K gamma --- PI3K delta 6-(4-Methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine Drug Info
VEGFR2 --- VEGFR1 6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidine Drug Info
H3 --- SERT N-methyl(2-(4-(methylthio)phenoxy)-4-(4-morpholinobut-1-ynyl)phenyl)methanamine Drug Info
EGFR3 --- HER2 N-[4-[(3-bromo-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(4-morpholinyl)-2-pentynamide Drug Info
PI3K gamma --- PI3K delta 4-[6-(4-Methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl]-phenylamine Drug Info
VEGFR2 --- VEGFR1 2-((5H-imidazo[4,5-c]pyridin-5-yl)methyl)-N-(4-isopropylphenyl)benzamide Drug Info
HD6 --- HDAC4 N-benzyl-N-methyl-4-(2,2,2-trifluoroacetyl)thiophene-2-carboxamide Drug Info
EGFR3 --- HER2 EGFR_ErbB_2_ErbB_4_Inhibitor Drug Info
PKCA --- NPKC delta 3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzoyl)-benzoic acid 2-(4-hydroxy-benzyl)-cyclopentyl ester Drug Info
VEGFR2 --- VEGFR1 (4-Chloro-phenyl)-(7-methyl-4-pyridin-4-ylmethyl-phthalazin-1-yl)-amine Drug Info
HDAC1 --- HD6 (2E,4E,8E)-9-Benzo[1,3]dioxol-5-yl-nona-2,4,8-trienoic acid hydroxylamine Drug Info
EGFR3 --- HER2 (R)-7-(4-(1-(4-Fluorophenyl)ethylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide Drug Info
PKCA --- NPKC delta 3,5-Dihydroxy-4-(2-hydroxy-6-methoxycarbonyl-benzoyl)-benzoic acid 3-(4-hydroxy-phenyl)-propyl ester Drug Info
VEGFR2 --- VEGFR1 N-(4-chlorophenyl)-4-(2-(quinolin-4-yl)ethyl)thiazole-5-carboxamide Drug Info
HDAC1 --- HD6 (S)-benzyl 1-(1-methyl-5-phenyl-1H-1,2,4-triazol-3-yl)-5-(sulfamoylamino)pentylcarbamate Drug Info
EGFR3 --- HER2 SID124350082 Drug Info
PKCA --- NPKC delta (2S,5S)-8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-1,4,5,6-tetrahydro-2H-benzo[e][1,4]diazocin-3-one Drug Info
VEGFR2 --- VEGFR1 N-(3,4-dichlorophenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazole-5-carboxamide Drug Info
HDAC1 --- HD6 (S)-benzyl 1-(4,5-diphenylthiazol-2-ylamino)-1-oxo-6-(sulfamoylamino)hexan-2-ylcarbamate Drug Info
EGFR3 --- HER2 2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-ylsulfanylmethyl)-phenyl]-acrylamide Drug Info

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