Target Pair Drug Name
Ftase --- FPTase 7-Bromo-1-(3H-imidazol-4-ylmethyl)-4-methanesulfonyl-3-phenethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine Drug Info
MMP2 --- MMP9 5-(4-Phenoxyphenyl)-5-(4-(cyclobutanecarbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione Drug Info
TRIP5 --- mRNA of KIF11 1-[4'-(trifluoromethyl)-4-biphenylyl]methanesulfonamide Drug Info
Ftase --- FPTase 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid 2-(2,2,2-trifluoro-ethyl)-benzyl ester Drug Info
MMP2 --- MMP9 methyl 4-(3-(N-hydroxyformamido)-4-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)butyl)benzoate Drug Info
TRIP5 --- mRNA of KIF11 (+/-)-Ethyl 1-(3-hydroxyphenyl)-2-acetyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylate Drug Info
Ftase --- FPTase 1-[4-(3-Cyclopropyl-10-methoxy-8-methyl-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone Drug Info
MMP2 --- MMP9 (S)-N-hydroxy-2-(isopropylamino)-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-2-ylsulfonamido)propanamide Drug Info
TRIP5 --- mRNA of KIF11 6-(3-hydroxyphenyl)-N,N-dimethyl-2,3,6,7-tetrahydrofuro[3,2-h]isoquinoline-8(9H)-carboxamide Drug Info
Ftase --- FPTase 5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-cyclopropylmethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile Drug Info
MMP2 --- MMP9 6-Benzyloxy-2-(2,5-dichloro-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide Drug Info
TRIP5 --- mRNA of KIF11 N-(3-aminopropyl)-N-(1-(3-benzyl-5-chloro-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)propyl)-4-chlorobenzamide Drug Info
Ftase --- FPTase methyl 10-cyano-23-oxo-8-oxa-1,15,17,21-tetraazapentacyclo[19.2.2.13,7.19,13.015,19]heptacosa-3(27),4,6,9(26),10,12,16,18-octaene-4-carboxylate Drug Info
MMP2 --- MMP9 5-[4-(4-Bromo-phenoxy)-phenyl]-5-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione Drug Info
Src --- VEGFR CHEMBL425209 Drug Info
Ftase --- FPTase (S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-phenethyl-amino]-methyl}-benzoylamino)-4-methylsulfanyl-butyric acid Drug Info
MMP2 --- MMP9 5-[4-(2-Bromo-ethyl)-piperazin-1-yl]-5-[4-(4-bromo-phenoxy)-phenyl]-pyrimidine-2,4,6-trione Drug Info
VEGFR1 --- FGFR1 2-(1H-indazol-3-yl)-5-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazole Drug Info
Ftase --- FPTase (S)-2-((S)-2-{[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentyl]-methyl-amino}-3-phenyl-propionylamino)-4-methylsulfanyl-butyric acid Drug Info
MMP2 --- MMP9 5-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-5-[4-(4-iodo-phenoxy)-phenyl]-pyrimidine-2,4,6-trione Drug Info
VEGFR2 --- AuroraA 4-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-pyrazol-4-yl)vinyl)isoquinoline Drug Info
Ftase --- FPTase (S)-2-({2'-Methyl-5-[((E)-2-pyridin-3-yl)-vinyl]-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid Drug Info
MMP2 --- MMP9 (6S,7S)-7-hydroxycarbamoyl-6-(3-phenyl-2,5-dihydro-pyrrole-1-carbonyl)-5-aza-spiro[2.5]octane-5-carboxylic acid methyl ester Drug Info
VEGFR2 --- CD135 (Z)-(5-{6-[3-(4-Methoxyphenyl)-ureido]-2-oxo-1,2-dihydroindol-3-ylidene-methyl}-2,4-dimethyl-1H-pyrrol-3-yl)acetic acid Drug Info
Ftase --- FPTase Lithium; (S)-2-({5-[5-(2-methoxy-phenyl)-furan-2-ylmethoxymethyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate Drug Info
MMP2 --- MMP9 (3R,4S)-1-(1-Methyl-1H-imidazole-4-sulfonyl)-piperidine-3,4-dicarboxylic acid 3-hydroxyamide 4-{[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-amide} Drug Info
VEGFR2 --- CDK1 N-((5-(3-(4-(methoxymethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)methyl)propan-1-amine Drug Info
Ftase --- FPTase (S)-2-(4-((R)-2-amino-3-mercaptopropylamino)benzamido)-4-(methylthio)butanoic acid Drug Info
MMP2 --- MMP9 5-[4-(4-Bromo-phenoxy)-phenyl]-5-[4-(4-nitro-phenyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione Drug Info
VEGFR2 --- CDK2 1-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-6,7-dihydro-2H-pyrano[3,4-c]pyrrol-4-one Drug Info
Ftase --- FPTase 6-[(3'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-5-(3-chloro-phenyl)-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile Drug Info
MMP2 --- MMP9 (-)-(R)-4-(4-chlorophenoxy)-N-(1-hydroxy-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)benzamide Drug Info
VEGFR2 --- Cmet N-(3-fluoro-4-(2-(furan-3-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Drug Info
Ftase --- FPTase (S)-2-(3-{[Benzoyl-(1H-imidazol-4-ylmethyl)-amino]-methyl}-benzoylamino)-4-methylsulfanyl-butyric acid Drug Info
MMP3 --- MMP8 2-(Hexadecane-1-sulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide Drug Info
VEGFR2 --- Cmet N-(3-fluoro-4-(2-(1-methyl-1H-1,2,4-triazol-5-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide Drug Info
Ftase --- FPTase 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(phenyl)-N'-cyano-piperidine-1-carboxamidine Drug Info
MMP3 --- MMP8 2-(5-Dimethylamino-naphthalene-1-sulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide Drug Info
VEGFR2 --- Cmet 1-(3-fluoro-4-(2-(furan-2-carbonyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-3-(2-phenylacetyl)thiourea Drug Info
Ftase --- FPTase C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-1-methyl-[1,2,4]triazolo[4,3-a]quinolin-7-yl]-C-(3-methyl-3H-imidazol-4-yl)-methylamine Drug Info
MMP3 --- MMP8 [2-(4-Methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-oxo-acetic acid Drug Info
VEGFR2 --- CSrc N-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-cyclopentylpropanamide Drug Info
Ftase --- FPTase 2-{2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-oxo-ethyl}-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one Drug Info
mTOR --- AKT (4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl){6-[(2R,3R)-2-(4-fluorophenyl)pyrrolidin-3-ylamino]pyrazin-2-yl}-methanone Drug Info
VEGFR2 --- CSrc [6-Methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-(4-methoxy-phenyl)-amine Drug Info
Ftase --- FPTase 4-(5-{[2-(3,5-Dichloro-phenyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile Drug Info
mTOR --- AKT 1-[(2R,3R)-3-[6-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]-pyrimidine-5-carbonyl)pyrazin-2-ylamino]-2-(4-fluorophenyl)-pyrrolidin-1-yl]ethanone Drug Info
VEGFR2 --- CSrc N-(4-methyl-3-(1-(6-(2-(pyridin-2-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide Drug Info
Ftase --- FPTase 4-[3-(4-Cyano-benzyl)-2-methyl-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid 2-trifluoromethoxy-benzyl ester Drug Info
mTOR --- PI3K gamma 5-(9-(1-(4-chlorobenzyl)piperidin-4-yl)-6-morpholino-9H-purin-2-yl)pyridin-3-ol Drug Info

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