Target Pair Drug Name
Ftase --- FPTase (S)-2-((S)-2-{[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentyl]-methyl-amino}-pentanoylamino)-4-hydroxy-butyric acid Drug Info
mTOR --- AKT trans-2-amino-8-((1r,4r)-4-hydroxycyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpteridin-7(8H)-one Drug Info
VEGFR2 --- CSrc 6-(2,6-dichlorophenyl)-2-((4-(4-methyl-1-piperazinyl)phenyl)amino)-pyrimido[5',4':5,6]pyrimido[1,2-a]-benzimidazol-5(6H)-one Drug Info
Ftase --- FPTase 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid 2-chloro-benzyl ester Drug Info
mTOR --- PI3K gamma 4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-indol-3-yl)methylene)benzofuran-3(2H)-one Drug Info
VEGFR2 --- CSrc (5-Chloro-benzofuran-4-yl)-[6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine Drug Info
Ftase --- FPTase 4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(3-phenyl-propionyl)-piperazine-2-carboxylic acid (pyridin-3-ylmethyl)-amide Drug Info
mTOR --- PI3K gamma (S)-1-(4-(4-(dimethylamino)piperidine-1-carbonyl)phenyl)-3-(4-(4-morpholino-6-(tetrahydrofuran-3-yloxy)-1,3,5-triazin-2-yl)phenyl)urea Drug Info
VEGFR2 --- EGFR3 (2E)-N-[4-({4-[(3-chlorobenzyl)oxy]-3,6-dioxocyclohexa-1,4-dien-1-yl}amino)-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide Drug Info
Ftase --- FPTase 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclopentylamide 2-[(pyridin-3-ylmethyl)-amide] Drug Info
mTOR --- PI3K gamma 4-(3-(4-(3-ethyl-7-morpholino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl)ureido)benzamide Drug Info
VEGFR2 --- FGFR1 3-(3,5-Dimethoxy-phenyl)-N*7*-[3-(4-methyl-piperazin-1-yl)-propyl]-[1,6]naphthyridine-2,7-diamine Drug Info
Ftase --- FPTase 2-[Amino-(4-chloro-phenyl)-(3-methyl-3H-imidazol-4-yl)-methyl]-9-(3-chloro-phenyl)-5-methyl-5,9-dihydro-8-thia-5-aza-benzocyclohepten-6-one Drug Info
mTOR --- PI3K gamma isopropyl 4-[6-(4-{[(2-fluoroethyl)carbamoyl]amino}phenyl)-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate Drug Info
VEGFR2 --- TEK N-(6-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)benzthiazol-2-yl)methanesulfonamide Drug Info
Ftase --- FPTase 4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid 1-methyl-piperidin-4-yl ester Drug Info
NET --- SERT SID533836 Drug Info
VEGFR2 --- TEK 7-Cyclopentyl-6-methyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine Drug Info
Ftase --- FPTase 2-[1-(3-Bromo-benzyl)-1H-indol-3-yl]-N-isopropyl-N-pyridin-4-ylmethyl-acetamide Drug Info
NET --- SERT 1-[3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]oct-2-yl]-propan-1-one Drug Info
VEGFR2 --- TEK 3-isopropyl-N-(3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)phenyl)benzamide Drug Info
Ftase --- FPTase (S)-2-(2-{[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentyl]-naphthalen-1-ylmethyl-amino}-acetylamino)-4-hydroxy-butyric acid Drug Info
NPKCdelta --- NPKCtheta 4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(piperidin-1-yl)prop-1-enyl)thieno[2,3-b]pyridine-5-carbonitrile Drug Info
VEGFR2 --- TEK N-(2-((3-(dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)benzamide Drug Info
Ftase --- FPTase 1-[3-Benzyl-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-ethanone Drug Info
NPKCdelta --- NPKCtheta 3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridin-2-yl)acrylamide Drug Info
VEGFR2 --- TEK 1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl)phenyl)-3-(2-fluoro-6-(trifluoromethyl)phenyl)urea Drug Info
Ftase --- FPTase 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-piperidin-4-yl-ethanone Drug Info
NPKCdelta --- NPKCtheta 5-(2-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile Drug Info
VEGFR2 --- TEK isopropyl 5-methyl-3-oxo-9-propyl-2,3,5,7,8,9-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-12-ylcarbamate Drug Info
Ftase --- FPTase (S)-2-((S)-2-{[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentyl]-benzyl-amino}-3-phenyl-propionylamino)-4-methylsulfanyl-butyric acid Drug Info
NPKCdelta --- NPKCtheta 5-(3-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile Drug Info
VEGFR2 --- TEK 4-fluoro-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide Drug Info
Ftase --- FPTase 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid 2-methoxy-pyridin-3-ylmethyl ester Drug Info
NPKCdelta --- NPKCtheta 5-(4-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile Drug Info
VEGFR2 --- VEGFR1 N-(4-bromophenyl)-4-(pyridin-4-ylmethylamino)isothiazole-3-carboxamide Drug Info
FTase --- GTase 5-((5-((2-(benzo[d][1,3]dioxol-5-yl)-4-cyanobenzyloxy)methyl)-1H-imidazol-1-yl)methyl)picolinonitrile Drug Info
CDK2 --- AuroraA 1-Methyl-8-[(4-morpholin-4-ylphenyl)amino]-4,5-dihydro-1Hpyrazolo[4,3-h]quinazoline-3-carboxamide Drug Info
NPKCdelta --- NPKCtheta 5-(5-((diethylamino)methyl)furan-2-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile Drug Info
VEGFR2 --- VEGFR1 4-(pyridin-3-ylmethylamino)-N-(3-(trifluoromethyl)phenyl)isothiazole-3-carboxamide Drug Info
H3 --- SERT 3-(4-(1-isopropylpiperidin-4-yloxy)phenyl)-N,N-dimethyl-3-phenoxypropan-1-amine Drug Info
EGFR3 --- HER2 N-(4-Benzyloxy-3-chloro-phenyl)-5-[5-(2-morpholin-4-yl-ethyl)-[1,3,4]oxadiazol-2-yl]-pyrimidine-4,6-diamine Drug Info
PI3K gamma --- PI3K delta henicosa-4,7,10,12,15,18-hexaenoic acid Drug Info
VEGFR2 --- VEGFR1 N-(4-chlorophenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-pyrazole-5-carboxamide Drug Info
H3 --- SERT 7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methoxyphenyl)-1,2,3,4-tetrahydro-2,6-naphthyridine Drug Info
EGFR3 --- HER2 6-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyhexanamide Drug Info
PI3K gamma --- PI3K delta 6,6-dimethyl-2-(6-(1-(pyridin-3-ylmethyl)-1H-pyrazol-4-yl)-2H-benzo[b][1,4]oxazin-4(3H)-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one Drug Info
VEGFR2 --- VEGFR1 5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazol-5-yl)-N-(4-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-amine Drug Info
H3 --- SERT 4-(4-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine Drug Info
EGFR3 --- HER2 2-(2-(4-Hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one Drug Info

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