Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- CDK4 | 4-[(3-Hydroxy-4-pyridin-3-yl-benzylamino)-methylene]-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 6-Acetyl-2-{5-[bis-(2-methoxy-ethyl)-amino]-pyridin-2-ylamino}-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | 1-[4-(5-Bromo-4-phenylamino-pyrimidin-2-ylamino)-phenoxy]-3-dimethylamino-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | (4Z)-{[(5-Furan-3-yl-4-hydroxy-pyridin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 6-Bromo-8-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | 1-[5-(tert-Butylamino-methyl)-1H-pyrazol-3-yl]-3-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea | Drug Info |
| CDK2 --- CDK4 | 4-(2-(2-fluoro-5-methylphenylamino)pyrimidin-4-yl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | 4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 4-[2-(3-Hydroxy-4-methyl-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | CHEMBL453655 | Drug Info |
| CDK2 --- CDK4 | 4-[(4-Furan-2-yl-3-hydroxy-benzylamino)-methylene]-6-iodo-4Hisoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | CHEMBL100391 | Drug Info |
| CDK2 --- CDK4 | 1-(5-Oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-(5-pyrrolidin-1-ylmethyl-1H-pyrazol-3-yl)-urea | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-2-(pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | [4-(2-Dimethylamino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | 1-Dimethylamino-3-{4-[4-(2-fluoro-5-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenoxy}-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-6-methoxymethyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | 1-(4-{5-Bromo-4-[phenyl-(4,4,4-trifluoro-butyl)-amino]-pyrimidin-2-ylamino}-phenoxy)-3-dimethylamino-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | 4-[2-(4-Fluoro-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | N-[4-(2-Amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-N',N'-dimethyl-benzene-1,4-diamine | Drug Info |
| CDK2 --- CDK4 | 4-[2-(3-Hydroxy-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | TCMDC-138697 | Drug Info |
| CDK2 --- CDK4 | CHEMBL317629 | Drug Info |
| CDK2 --- CDK4 | CHEMBL478409 | Drug Info |
| CDK2 --- CDK4 | Benzo[1,3]dioxol-5-yl-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | N-(3-((diethylamino)methyl)phenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL421583 | Drug Info |
| CDK2 --- CDK4 | 6-tert-Butyl-4-{[(4-hydroxy-5-phenyl-pyridin-2-ylmethyl)-amino]-methylene}-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 6-Iodo-4-{[(4-hydroxy-5-methoxy-pyridin-2-ylmethyl)-amino]-methylene}-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 4-[2-(4-Fluoro-3-methyl-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | N-(4-(benzylsulfonyl)phenyl)-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL430507 | Drug Info |
| CDK2 --- CDK4 | (4Z)-4-{[(3-Hydroxy-4-propoxybenzyl)amino]methylene}-6-iodoisoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | N-(2-(diethylamino)ethyl)-3-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzamide | Drug Info |
| CDK2 --- CDK4 | 3-[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol | Drug Info |
| CDK2 --- CDK4 | 1-Dimethylamino-3-{4-[4-(2-fluoro-phenylamino)-pyrimidin-2-ylamino]-phenoxy}-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | GW781673X | Drug Info |
| CDK2 --- CDK4 | (3-Methoxy-5-trifluoromethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | N-(5-(2-(cyclohexyloxy)-5-methylpyrimidin-4-yl)thiazol-2-yl)pyridin-2-amine | Drug Info |
| CDK2 --- CDK4 | 3-[4-(4-Methyl-2-methylamino-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol | Drug Info |
| CDK2 --- CDK4 | N-[(4Z)-1,3-Dioxo-4-({[4-piperidin-1-ylmethyl]phenyl}amino)-methylene]-1,2,3,4-tetrahydroisoquinolin-6-yl]acetamide | Drug Info |
| CDK2 --- CDK4 | 4-(4-(2,4-dimethylthiazol-5-yl)pyrimidin-2-ylamino)phenol | Drug Info |
| CDK2 --- CDK4 | [4-(2,4-Dimethyl-1H-pyrrol-3-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL485240 | Drug Info |
| CDK2 --- CDK4 | [4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-[5-(3,3-dimethyl-piperazin-1-yl)-pyridin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL99689 | Drug Info |
| CDK2 --- CDK4 | CHEMBL485618 | Drug Info |
| CDK2 --- CDK4 | N-(4-nitrophenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine | Drug Info |
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