Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- CDK4 | 4-[(3-Hydroxy-4-pyridin-3-yl-benzylamino)-methylene]-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 3,5-Dimethyl-4-[2-(3-nitro-phenylamino)-pyrimidin-4-yl]-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | (3-Bromo-5-trifluoromethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | (4Z)-6-Fluoro-4-{[(3-hydroxy-4-methoxybenzyl)amino]methylene}-isoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | 3-[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-ylamino]-benzonitrile | Drug Info |
| CDK2 --- CDK4 | (4Z)-4-{[(4-Amino-3-hydroxybenzyl)amino]methylene}-6-bromoisoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | [4-(2-Allylamino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | (4-Chloro-3-trifluoromethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | [4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-[5-((R)-3-methyl-piperazin-1-ylmethyl)-pyridin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 4-[(3-Hydroxy-4-methoxy-benzylamino)-methylene]-6-methoxy-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 4-(4-(2-amino-4-methylthiazol-5-yl)pyrimidin-2-ylamino)phenol | Drug Info |
| CDK2 --- CDK4 | CHEMBL457888 | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-6-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | (4Z)-6-Bromo-4-({[(2-oxo-1,2-dihydropyridin-4-yl)methyl]amino}methylene) isoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | 3,5-Dimethyl-4-[2-(4-methyl-3-nitro-phenylamino)-pyrimidin-4-yl]-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | CHEMBL515839 | Drug Info |
| CDK2 --- CDK4 | (3,5-Dichloro-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | 4-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzoic acid | Drug Info |
| CDK2 --- CDK4 | [4-(5-Bromo-2,4-dimethyl-1H-pyrrol-3-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | N,4-dimethyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)thiazol-2-amine | Drug Info |
| CDK2 --- CDK4 | (3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | 4-{[(6-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | CHEMBL515854 | Drug Info |
| CDK2 --- CDK4 | 8-Cyclohexyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | TCMDC-138687 | Drug Info |
| CDK2 --- CDK4 | CHEMBL101473 | Drug Info |
| CDK2 --- CDK4 | (15R,18S)-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaene-3,5-dione | Drug Info |
| CDK2 --- CDK4 | GW683003X | Drug Info |
| CDK2 --- CDK4 | [4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-phenyl-amine | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-5-methyl-7-oxo-2-(4-piperazin-1-yl-phenylamino)-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid methyl ester | Drug Info |
| CDK2 --- CDK4 | (8-Isopropyl-7-methoxy-quinazolin-2-yl)-(4-pyrrolidin-1-yl-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | 1-(5-Cyclopentylaminomethyl-1H-pyrazol-3-yl)-3-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea | Drug Info |
| CDK2 --- CDK4 | [4-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-yl]-phenyl-amine | Drug Info |
| CDK2 --- CDK4 | 6-Acetyl-2-{5-[bis-(2-methoxy-ethyl)-amino]-pyridin-2-ylamino}-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | 1-[4-(5-Bromo-4-phenylamino-pyrimidin-2-ylamino)-phenoxy]-3-dimethylamino-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | (4Z)-{[(5-Furan-3-yl-4-hydroxy-pyridin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 6-Bromo-8-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | 1-[5-(tert-Butylamino-methyl)-1H-pyrazol-3-yl]-3-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea | Drug Info |
| CDK2 --- CDK4 | 4-(2-(2-fluoro-5-methylphenylamino)pyrimidin-4-yl)benzenesulfonamide | Drug Info |
| CDK2 --- CDK4 | 4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 4-[2-(3-Hydroxy-4-methyl-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | CHEMBL453655 | Drug Info |
| CDK2 --- CDK4 | 4-[(4-Furan-2-yl-3-hydroxy-benzylamino)-methylene]-6-iodo-4Hisoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | CHEMBL100391 | Drug Info |
| CDK2 --- CDK4 | 1-(5-Oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-(5-pyrrolidin-1-ylmethyl-1H-pyrazol-3-yl)-urea | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-2-(pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | [4-(2-Dimethylamino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | 1-Dimethylamino-3-{4-[4-(2-fluoro-5-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenoxy}-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-6-methoxymethyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | 1-(4-{5-Bromo-4-[phenyl-(4,4,4-trifluoro-butyl)-amino]-pyrimidin-2-ylamino}-phenoxy)-3-dimethylamino-propan-2-ol | Drug Info |
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